Workshop for Handling and Care of Laboratory Animals”
in association with
CPCSEA, Ministry of Environment, Forest & Climate Change
Government of India (Animal Welfare Division), New Delhi
February 11-14, 2016
For more information please visit: http://www.jnu.ac.in/Conference/...
From touring leading research institutes in Germany to meeting 25 Nobel Laureates from different fields of science and research, the Lindau Meet and Post-Lindau Tour is every young researcher's dream come true. Every year a group of young Indian scientists from a particular subject are chosen from institutes across the country to attend the two-week long programme. All expenses for the group are jointly covered by the Department of Science and Technology (DST) and the German Research Foundation (DFG)....
School of Life Sciences
in association with
University of Colorado, Denver, USA
University of Oklahoma Health Sciences, Oklahoma, USA
University of Pittsburgh Canc...
Nature India is proud to be associated with Jawaharlal Nehru University (JNU), New Delhi as media partner of the just concluded International Symposium on Current Advances in Radiobiology, Stem Cells and Cancer Research (February 19-21, 2015).
Extracts from plants ranging from cabbages to figs are offering new clues for prevention or improvement of breast cancer treatment. Several plant chemicals or phytochemicals are being tested for their ability to arrest the growth of breast cancer cells in animal models, according to scientists attending an international conference on cancer research in New Delhi.
The three-day conference on 'Current Advances in Radiobiology, Stem Cells and Cancer Research' (February 19-21, 2015) heard about the effects of three pla...
The main areas of interest of Prof. Singh’s lab are understanding the mechanisms of carcinogenesis development to find novel targets which could be affected by natural agents, to inhibit cancer progression and metastasis. The laboratory’s efforts have been largely devoted towards not only screening natural compounds/ chemopreventive agents for their efficacy, but also providing mechanistic insights into their mode of action.
Discovering and evaluating anticancer activities of small molecules (phytochemicals) and providing scientific basis (mechanisms) for their effectiveness in controlling carcinogenesis is a priority area of research. The goal is to develop mechanism-based non-toxic anticancer agents for their potential use in cancer chemoprevention and treatment. The lab though in its early years of establishment has done significant work in studying natural compounds with anti-angiogenic efficacies. The laboratory has established good in vitro, in vivo and ex-vivo model systems to study modulation of tumor angiogenesis by these plant compounds.
Evaluating these phytochemicals for potential synergism with existing, well-established chemo-and radiotherapy regimens is also a significant focus of the lab.Along with these studies, the lab also tries to understand biological processes, which get deregulated during cancer development including mitogenic, and cell survival signaling, apoptosis and DNA damage/repair.
Other than mammalian cell-culture and rodent models, we are also working on establishing other model systems includingDrosophila Melanogaster model, which are easier for manipulation and would give us plausible explanations or cues that can be extrapolated to derive an understanding of the carcinogenesis development.
To study to interaction of mitochondrial dynamics related proteins
Examining the chemopreventive and therapeutic effects of novel phyt
To study the chemopreventive and chemotherapeutic effects of dially
Angiogenesis is essential for the grow
Effect of phytochemicals on epigenetic modifications in cancer.
Effect of phytochemical(s) in modulating DNA damage and repair mech
Arsenic and cancer chemoprevention
Mechanism of cancer prevention and therapy employing dietary agents
To fight against cancer or any other agents we need to boost our im
Alteration of oligosaccharide on cell surface protein occurs in can
Drug resistance, cancer chemoprevention
The role of neurotransmitters in the brain tumor is now becoming a
As chemoprevention and chemotherapy are two important regimen for c
Investigating the effects of phytochemicals in cancer chemopreventi
Phytochemicals and its anti-inflammatory responses on cancer cells.