To study to interaction of mitochondrial dynamics related proteins with tumor regulators to understand their role in cancer progression.
Examining the chemopreventive and therapeutic effects of novel phytochemicals using various pre-clinical models of liver cancer, and associated mechanisms of action, especially apoptosis, cell cycle and cell signal-modulatory effects.
To study the chemopreventive and chemotherapeutic effects of diallyltrisulfide on head and neck squamous cell carcinoma both in vitro and in vivo. Objectives of my study includes examining the effects of DATS on cell proliferation, cell death and apopt
Angiogenesis is essential for the growth and progression of solid tumors beyond the size limit of 1-2 mm3 diameter. To obtain the blood supply, tumor cells shift the balance more the towards stimulatory pro-angiogenic molec
Effect of phytochemicals on epigenetic modifications in cancer.
Effect of phytochemical(s) in modulating DNA damage and repair mechanisms in cancer cells
Arsenic and cancer chemoprevention
The identification of phytochemicals, dietry and non dietry agents that exhibit efficacy in the prevention of cancer and dissect their mechanisms, target pathways in cancer cells and exploit the molecular and biochemical properties of these components
Chemoprevention of cancer has been shown as good promising approach against many cancers. Here I am investigating the effect of usnic acid on growth and progression of lung cancer.
Mechanism of cancer prevention and therapy employing dietary agents: Oncogenes and tumor suppressor genes, cell cycle regulation, p53, cyclins, cyclin dependent kinases, cyclin dependent kinase inhibitors, DNA damage and apoptosis.
To fight against cancer or any other agents we need to boost our immune system. Phytochemicals have their different mechanisms of action in regulating cancer cells survival and death. Besides this we are trying to find out the role of phytochemicals in
Alteration of oligosaccharide on cell surface protein occurs in cancer. Target this altered Pattern of glycan chain by phytochemicals and develop novel strategy for diagnosis of cancer without any side effect.
Drug resistance, cancer chemoprevention
The role of neurotransmitters in the brain tumor is now becoming a very attracting field of study. My study focus on using phytochemicals on glioblastoma cells which target the neurotransmitter receptors. I want to examine how these phytochemicals will
As chemoprevention and chemotherapy are two important regimen for cancer treatment, I have intense curiosity to explore clinically potential phytochemical (like berberine) for their mechanisms and targets to prevent and/or cure breast cancer.
Investigating the effects of phytochemicals in cancer chemoprevention and targeting epithelial mesenchymal transition in breast cancer cells.
Phytochemicals and its anti-inflammatory responses on cancer cells.