Research Projects
Over the years, significant research projects have been conducted to explore innovative solutions in the field of cancer treatment and prevention, supported by various funding agencies across India and abroad. One such project, funded by the Ministry of AYUSH, Govt. of India, from 2018 to 2021, focused on studying Unani medicine formulations to evaluate their anticancer efficacy and mechanisms. Another project, funded by the Department of Science and Technology (DST) India, during the same period, aimed at developing single-cell derived clonal spheroids as a novel tool for drug discovery in cancer research.
From 2017 to 2019, under the UPE-II Scheme (UGC/JNU), researchers developed a prototype sunscreen and antiaging lotion based on silibinin and Aloe vera. This period also saw investigations into the cancer chemopreventive activities of the dietary flavonol fisetin, with funding from the DST India (2017-2020). Moreover, a project exploring the epigenetic changes and cancer risks due to microgravity exposure was carried out from 2014 to 2019, also under the UPE-II Scheme (UGC/JNU).
Between 2012 and 2015, the Indian Council of Medical Research funded a study on the anti-angiogenic and anti-tumor effects of fisetin in lung cancer, providing insights into potential cancer interventions. Another project during this period, supported by the University Grants Commission (UGC) India, investigated the role of protein glycosylation in cell-extracellular matrix interactions and cancer progression.
In addition, a project on combination therapy in in-vivo and in-vitro model systems was conducted from 2016 to 2018 with support from the Department of Biotechnology (DBT) India. Earlier, from 2009 to 2012, research on the antiangiogenic effects and mechanisms of acacetin, with potential implications for cancer control, was funded by the Council of Scientific and Industrial Research (CSIR), India. Lastly, between 2008 and 2011, the DST India supported a project targeting cell signaling and cell cycle progression to intervene in prostate cancer using decursin.
These projects collectively contribute to the growing body of knowledge in cancer research, with the potential to significantly impact future therapeutic strategies.